Page 321 - ATP-P 11th Ed

Contraindications:
• Do not take the following medicines with lopinavir and ritonavir (Kaletra ) because
®
they can cause serious problems or death.
®
° Triazolam (Halcion )
®
° Astemizole (Hismanal )
®
° Pimozide (Orap )
®
° Cisapride (Propulsid )
®
° Terfenadine (Seldane ) – withdrawn from the U.S. market
° Midazolam
®
®
®
®
° Rifampin (Rimactane , Rifadin , Rifater , or Rifamate )
° Cholesterol-lowering medicines
• Lovastatin (Mevacor )
®
• Simvastatin (Zocor )
®
• Atorvastatin (Lipitor )
®
Pregnancy Category C
Side-effects/precautions:
• Body as a whole SECTION 3
° Allergic reaction, back pain, chest pain, chest pain substernal, cyst, drug interaction,
drug level increased, face edema, flu syndrome, hypertrophy, infection bacterial, mal-
aise, neoplasm, and viral infection
• Cardiovascular system
° Atrial fibrillation, cerebral infarct, deep vein thrombosis, migraine, myocardial infarct,
palpitation, postural hypotension, thrombophlebitis, varicose vein, and vasculitis
• Digestive system
° Cholangitis, cholecystitis, constipation, dry mouth, enteritis, enterocolitis, eructation,
esophagitis, fecal incontinence, gastritis, gastroenteritis, hemorrhagic colitis, hepatitis,
hepatomegaly, increased appetite, jaundice, liver fatty deposit, liver tenderness, mouth
ulceration, pancreatitis, periodontitis, sialadenitis, stomatitis, and ulcerative stomatitis
• Endocrine system
° Cushing’s syndrome, diabetes mellitus, and hypothyroidism
• Heme and lymphatic system
° Anemia, leukopenia, and lymphadenopathy
• Metabolic and nutritional disorders
° Avitaminosis, dehydration, edema, glucose tolerance decreased, lactic acidosis, obe-
sity, peripheral edema, and weight gain
• Musculoskeletal system
° Arthralgia, arthrosis, bone necrosis, joint disorder, and myasthenia
• Nervous system
° Abnormal dreams, agitation, amnesia, anxiety, apathy, ataxia, confusion, convulsion,
dizziness, dyskinesia, emotional lability, encephalopathy, extrapyramidal syndrome,

ATP-P Handbook 11th Edition 311