Page 316 - ATP-P 11th Ed

Fluconazole (Diflucan )
®
Aviation personnel are grounded for the initial 24hr of antifungal therapy and until
the medical condition no longer interferes with safely performing aviation duties and the
patient is free of side-effects.
Description: Synthetic triazole antifungal agent
Indications:
• Vaginal candidiasis (vaginal yeast infections due to Candida).
• Oropharyngeal and esophageal candidiasis.
• Fungal skin infections
Dose:
• Skin infection: 150mg, 1 pill per week × 4 weeks
• Single dose: Vaginal candidiasis: The recommended dosage of fluconazole for vaginal
candidiasis is 150mg as a single oral dose.
• Oropharyngeal candidiasis: The recommended dosage of fluconazole for oropharyngeal
SECTION 3 of oropharyngeal candidiasis generally resolves within several days, but treatment
candidiasis is 200mg on the first day, followed by 100mg once daily. Clinical evidence
should be continued for at least 2 weeks to decrease the likelihood of relapse.
Contraindications: Hypersensitivity to fluconazole
Pregnancy Category C
Side-effects/adverse reactions:
• Dermatologic
° Exfoliative skin disorders including Stevens-Johnson syndrome and toxic epidermal
necrosis.
TMEP use: Fungal Skin Infection Protocol

Fosphenytoin (Cerebyx )
®
GROUNDING medication for personnel on flight status
Description: Parenteral phenytoin
Indications: Prevention and treatment of seizures
Dose: 18mg/kg IV/IO at 100–150mg/min if available for seizures refractory to benzodiazepines
• Do not administer faster than 150mg/min since this may result in hypotension.
Contraindications:
• Hypersensitivity to phenytoin
• Sinus bradycardia
• AV block
Pregnancy Category D
Adverse effects: Hypotension with rapid IV administration

306 SECTION 3 RECOMMENDED DRUG LIST (RDL)