Page 314 - ATP-P 11th Ed

• May be administered IV up to 14 days or IM injection for up to 7 days
• For IV administration, infuse over 30min
Pediatric dose: Not approved in patients <18 years
K9 Dose: 15mg/kg IV/IM bid. Do not exceed 1g in a 24 hour period.
Contraindications:
• Hypersensitivity to ertapenem
• Penicillin allergy with documented severe reaction to PCN
• Hypersensitivity to other carbapenem antibiotics
• Anaphylactic reactions to other beta-lactam antibiotics
• IM: hypersensitivity to lidocaine or other anesthetics of amide-type
Pregnancy Category B
Side-effects:
• Diarrhea
• Infused vein phlebitis/thrombophlebitis
• Nausea/vomiting
SECTION 3 • Vaginitis
• Headache
Adverse reactions: Seizures
Other notes:
• Visually inspect any solution of ertapenem for particulate matter and discoloration prior
to use when possible. Solutions range in color from colorless to pale yellow. Variations
in color do not affect potency of the drug.
• IV administration – must be reconstituted prior to administration.
° Do not mix or co-infuse with other medications.
° Do not use diluents containing dextrose.
° Reconstitute the contents of a 1g vial of ertapenem with 10mL of 0.9% NaCl, or bac-
teriostatic water for injection.
° Shake well to dissolve, and immediately transfer contents to 50mL of 0.9% NaCl.
° Complete infusion within 6hr of reconstitution.
• IM administration – must be reconstituted prior to administration.
° Reconstitute the contents of a 1g vial of ertapenem with 3.2mL of 1% lidocaine HCl
injection (without epinephrine). Shake vial thoroughly to form solution.
° Immediately withdraw the contents of the vial, and administer by deep IM injection
into a large muscle mass (such as the gluteal muscles or lateral part of the thigh).
° Use the reconstituted IM solution within 1 hour after preparation. DO NOT ADMIN-
ISTER THE RECONSTITUTED IM SOLUTION IV.
TMEP use:
• Abdominal Pain Protocol
• Bronchitis/Pneumonia Protocol
• Cellulitis/Cutaneous Abscess Protocol

304 SECTION 3 RECOMMENDED DRUG LIST (RDL)