Page 330 - ATP-P 11th Ed

• Trichomoniasis – 2g PO × 1 dose; OR 250mg PO tid × 7 days
• Giardia – 250mg PO tid × 5–7 days
• Severe anaerobic infections – 1g IV, then 500mg IV q6hr
Pediatric dose:
• Safety and efficacy have not been established, except for amebiasis. 35–50mg/kg tid for
10 days. Newborns exhibit a reduced capacity to eliminate the drug.
K9 Dose: 15mg/kg
Contraindications:
• Hypersensitivity to any component of product, or other nitroimidazole derivatives
• Pregnancy (first trimester in patients with trichomoniasis)
• Administer with caution to patients with CNS diseases.
• Use with caution in patients with history of blood dyscrasias.
Pregnancy Category B
Side-effects: Disulfiram-like reaction including flushing, palpitations, tachycardia, nausea,
vomiting may occur with concomitant ethanol ingestion. Refrain from ethanol during ther-
SECTION 3 Adverse reactions:
apy and ≥1 to 3 days afterward.
• Seizures
• Peripheral neuropathy (numbness or paresthesia of extremity)
• Patients with undiagnosed candidiasis may present more prominent symptoms during
therapy; treat with candicidal agent.
TMEP use:
• Abdominal Pain Protocol
• Gastroenteritis Protocol

Midazolam
GROUNDING medication for personnel on flight status
Class: Benzodiazepine
Indications:
• Sedation in combination with analgesia to perform brief, but painful procedures (i.e.
fracture reduction)
• Adjunct to ketamine sedation
• Treatment of active seizures
• Sedation of agitated patients
Dose:
• 0.07–0.08mg/kg IM (Average or typical adult dose is 5mg IM)
• 5–10mg IN/IM/IV/IO for seizure control
• 1–2mg IV slowly q2–3min to maximum adult dose of 10mg for sedation purposes. Titrate
to achieve necessary level. (The patient is somewhat somnolent, but still easily arousable.)

320 SECTION 3 RECOMMENDED DRUG LIST (RDL)