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This patient clearly needs fluid resuscitation. However, a pas-  •  May need morphine 2–4mg IV every 3–4h, as needed for
              sive leg raise (PLR) test can be performed to assess the need for   pain control. If hypotension develops after morphine, the
              fluid resuscitation after initial resuscitation, as the maneuver   patient is likely under-resuscitated and needs an IV fluid
              provides a temporary natural fluid bolus by returning venous   bolus.
              blood to the central circulation. It is ideally assessed with ad-  •  If the patient has persistent pain and tolerates oral (give in-
              vanced hemodynamic monitoring (beyond a BP cuff) but may   stead of acetaminophen): acetaminophen/codeine (300mg/
              be a valuable physical exam tool during PCC (Box 1). 19  30mg): 1–2 tabs orally every 4–6h, as needed. (Note: no
                                                                   other oral narcotic medication is available on DDG).
              Time +90min
              •  3L NS given, antibiotics given, IV fluids rate: NS at 125mL/h.  Chemical Venous Thromboembolism (VTE) Prophylaxis:
              •  HR 120bpm; BP 87/55mmHg; RR 25 breaths/min; SpO    •  Minimum: aspirin (oral).
                                                             2
                92% on room air; temp 39.5°C.                    •  Better: heparin 5,000 units subcutaneously three times a
              •  Urine output 15mL (dark in color).                day. (Note: Heparin is not available on DDG. Heparin is
              •  Alert and oriented, answering questions appropriately.  preferred in patients with renal insufficiency).
              •  White blood cell count (WBC): 21,000/μL; hemoglobin   •  Best: enoxaparin 30mg subcutaneously daily. (Note: only
                (Hgb) 15g/dL; hematocrit (HCT) 45%; platelet count (Plt)   10 doses of 30mg injection are available on DDG).  Use
                485,000/μL.                                        with telemedicine consultation. Use with caution if there
              •  Abdomen is still distended with persistent nausea and three   are renal impairment concerns.
                episodes of emesis. (Ileus or small bowel obstruction re-
                lated to intra-abdominal abscess).               Nausea/Vomiting
                                                                 •  Consider ondansetron: 1–2 tabs oral/sublingual every 4–6h
              The recommended interventions include:               as needed; or 4mg IV, may repeat once in 2h if nausea/
              •  Nasogastric tube placement. (Note: not available on DDG).  emesis returns.
              •  Urinary catheter placement for urine output (UOP) moni-  •  Check the QT interval on the monitor/electrocardiogram
                toring. Goal UOP: 0.3–0.5mL/kg/h.                  before considering ondansetron administration because
              •  Telemedicine consultation. Start vasopressors If available.  blood electrolytes may be abnormal with nausea or vom-
              •  Initiate vasopressors. Norepinephrine is preferred. Titrate   iting.  (Note: No electrocardiogram or three-lead cardiac
                to goal MAP >65mmHg. Vasopressors should be adminis-  monitoring is available on DDG).
                tered by role-based approved protocols or teleconsultation   •  Gastrointestinal prophylaxis medications are probably not
                approval.                                          indicated in this patient. If the patient requires intubation,
              •  Norepinephrine drip range: 2–20μg/min, titrate up or down   he may benefit from such medications. Minimum: raniti-
                by 2μg every 2–5min as needed (pro re nata or as needed).   dine or famotidine oral. Better: omeprazole oral. Best: pan-
                Onset: rapid, peak: 1–2min. (Note: not available on DDG).  toprazole IV/oral or H  receptor blockers IV/oral. (Note:
                                                                                     2
              •  Epinephrine drip range (Table 2): 1–10μg/min, titrate up   not available on DDG).
                or down by 1μg. Onset: rapid, peak: 1–2min. (Note: only
                epinephrine 1:1000 vials on DDG). To dilute to 1:10,000,   Routine Nursing Care
                mix 1mg/mL ampule (1:1000) with 9mL of NS.       •  Plan for nursing and daily progress note documentation. 20
              •  Ensure unimpeded flow of vasopressor and check IV site   •  Document full assessment and nursing progress notes for
                frequently for any signs of extravasation (blanching of skin   significant events, as needed.
                over vein, hardness of vein, and pallor to extremity). Check   •  Maintain head of bed elevation >30 degrees.
                the IV site that is infusing vasopressor hourly.  •  After initiating vasopressors, BP readings need to be taken
              •  Label the bag with the type of medication, concentration,   every 5min for proper titration for the first 30min and then
                and the time and date initiated.                   every 15–30min for the next 2–3h.  All other vital signs
              •  Other medications may be advisable based on the recom-  should be recorded hourly.
                mendations below.                                •  Depending on the patient’s ability to move, consider reposi-
                                                                   tioning every 2h. Given that vasopressors are currently being
              Pain control:                                        titrated, the patient is not likely a candidate for ambulation.
              •  Acetaminophen for pain control (it has no benefit for treating
                fever unless pyrexia; temp >39.5°C). Max dose 1g every 6h.  Time: +8h
              •  Avoid non-steroidal anti-inflammatory drugs (NSAIDs) such   •  HR 110 bpm; BP 98/66mmHg; RR 25 breaths/min; O  sat-
                                                                                                             2
                as ibuprofen due to the risk of renal impairment.  uration 96% on room air; temp 38.5°C.
              TABLE 2  Epinephrine 4μg/min (1:10,000) Bag Reference Chart*
                Normal saline bag size  Add to bag epinephrine   Starting dose,    Drip set: 10 drops/mL  Drip set: 15 drops/mL
                   (0.9% NaCl)          1:10,000             μg/min         Drip rate: drops/min   Drip date: drops/min
                      50mL             1mL (100μg)             4              20 drops/min        30 drops/min
                     100mL             2mL (200μg)             4              20 drops/min        30 drops/min
                     250mL             5mL (500μg)             4              20 drops/min        30 drops/min
                     500mL             10mL (1mg)              4              20 drops/min        30 drops/min
                   1000mL (1L)         20mL (2mg) †            4              20 drops/min        30 drops/min
              *Adapted from Prolonged Casualty Care Clinical Practice Guidelines. 5,9
              † Not recommended. Commits a high volume of epinephrine to a large bag of intravenous fluids; may waste intravenous fluids if epinephrine
              needs to be discontinued.
              NaCL = sodium chloride.

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