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FIGURE 3  Non-suicide hospital trauma fatalities for Operation   equivalents (CFR, %prehospital deaths, %hospital deaths, PS,
              Inherent Resolve (OIR) in Iraq and Operation Freedom’s Sentinel   PP, PS-CFR, PP-CFR). Because survivability and prevention of
              (OFS) in Afghanistan.                              fatalities resulting from non- homicide manners of death (ac-
                                                                 cident, natural causes, suicide) are inherently different from
                                                                 battle injury and homicide manner of death, we also recom-
                                                                 mend  tracking  the  proportionate  mortality  from  accident,
                                                                 natural causes, and suicide along with combat casualty care
                                                                 statistics. If the proportionate mortality from accident, natu-
                                                                 ral causes, and suicide increases dramatically, as was the case
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                                                                 during OIR,  then this warrants strategies to reduce mortality
                                                                 from these DNBI manners of death.
                                                                 Summary and Conclusion

                                                                 The majority of U.S. military combat fatalities have injuries
              deaths (KIA) misclassified as in-hospital deaths (DOW), thus   deemed non-survivable. In addition to promoting advance-
              artificially inflating the %DOW. This was caused by patients   ments in all aspects of medical care, medical and non-medical
              dead on arrival and patients with no return of spontaneous   leaders should strongly advocate for improving survival us-
              circulation after hospital arrival being classified as DOW when   ing primary and secondary prevention strategies that prevent
              they were in fact KIA. Furthermore, 42% of hospital fatali-  injury or reduce injury severity. This may be especially ap-
              ties in OFS and OIR  were deemed to have PS injuries after   propriate during a conflict that lasts decades, requires Service-
                              14
              the Military Trauma Mortality Review process was completed   members to deploy multiple times, and places them at higher
              (Figure 3).                                        risk for chronic disease and premature mortality.
              Not surprisingly, compared with prehospital combat deaths   Accurate and complete data capture, from the point of injury
              (where a casualty dies rapidly from a likely NS injury), a dis-  through hospitalization and rehabilitation must be a priority
              proportionate number of fatalities with PS battle injuries and   in any future conflict. This includes collecting and analyzing
              PP deaths occurred in hospital. 12–14  In our opinion, when the   data on all deaths using timely and comprehensive autopsies
              %DOW is compared longitudinally (e.g., over time, between   that  incorporate  advanced  radiologic  techniques.  In  addi-
              subgroups of interest, etc.), a fair comparison requires inclu-  tion to using these data for performance improvement, data
              sion of only casualties with PS battle injuries. Otherwise, it is   along with recommendations should be shared with medical
              not possible to determine whether an increase in %DOW is   and non-medical leadership in near real time to inform deci-
              due to an increase in fatalities with PS battle injuries or sim-  sion-making. The integration of mortality review statistics can
              ply an increase in the number of casualties arriving with NS   elucidate injury survivability and death preventability.  This
              battle injuries, systematic administrative misclassifications of   revised framework, alongside continuous mortality surveil-
              KIAs as DOWs, etc. Therefore, while specific focus on an in-  lance, may lead to an improved understanding of medical and
              crease in %DOW is worthwhile to identify opportunities to   non-medical solutions to save lives and eliminate preventable
              improve hospital trauma care, this statistic must be supple-  death.
              mented with accompanying timely mortality reviews. In terms
              of mass casualty events and large-scale combat operations, any   Acknowledgments
              significant increase in the number of casualties or delays in   The authors would like to acknowledge past and present per-
              casualty transport to a surgical capability can affect %DOW.   sonnel from the Armed Forces Medical Examiner System and
              For example, if prehospital casualty transport is significantly   Joint Trauma System for their efforts to improve morbidity
              delayed, the hospital %DOW may actually improve as more   and mortality in military casualties, and thus “Make Good
              critical casualties die before arriving at a hospital. Yet, such an   from the Bad.”
              improvement in %DOW would have nothing to do with any
              changes to hospital care.                          Author Contributions
                                                                 JCJ, RSK, JTH, and ELM conceived the concept and design
                                                                 of the commentary.  All  authors assisted in the acquisition,
              Disease and Non-Battle Injury Death
                                                                 analysis, and interpretation of data. JCJ, RSK, JTH, and ELM
              These aggregate statistics (e.g., CFR, %DOW, %KIA) by   contributed to the initial draft of the manuscript. All authors
              definition exclude non-battle injuries and deaths. A separate   revised the manuscript for critically important intellectual con-
              statistic, DNBI has long been used to describe the important   tent. All authors read and approved the final version of the
              role of military medicine in reducing preventable deaths for all   manuscript to be published.
              deployed  Servicemembers.  Non-battle  injuries  account  for  1
              in 3 injuries sustained in the deployed setting.  Further, these   Disclaimer
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              non-battle injuries along with disease from natural causes and   The views, opinions, and findings contained in this article are
              suicide account for approximately 1 in 5 deaths of Servicemem-  those of the authors and should not be construed as official or
              bers deployed in the theater of conflict.  DNBI has historically   reflecting views of the Department of Defense unless otherwise
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              been a leading cause of death on the battlefield but has gener-  stated.
              ally declined in more recent conflicts. As the goal of military
              medicine is to reduce death from all causes, metrics and mortal-  Disclosures
              ity reviews for DNBI should receive renewed attention. It is for   Dr.  John  Holcomb  is  on  the  board  of  directors  of  Decisio
              this reason we also recommend the use of the non-battle injury   Health, CCJ Medical Devices, QinFlow, Hemostatics, Zibrio

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