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TABLE 1  STEAM Capability Overlap and Integration With PCC   Financial Disclosure
              Guidelines                                         The authors Pierce, Stevens, and Tilley are listed as inventors
              Convergent Properties        Emergent Properties   for the STEAM device, patent pending. These authors are enti-
              Ability to heat and humidify   Inspiratory air temperature and   tled to future royalties related to STEAM.
              input air               humidity control
              ventilator and manual BVM   Telemetry capability   Funding
              compatibility                                      This work was supported by the Uniformed Services  Uni-
              intermediate and advanced   Breath rate control function  versity of the Health Sciences (USUHS) Medical Innovations
              airway compatibility                               Interest Group, USU School of Medicine Capstone Program,
              CO  capnography         Breath volume control function
                 2                                               The Henry M. Jackson Foundation for the Advancement of
              Barometric weather station  Output pressure limiting   Military Medicine, Inc., and the US Army Medical Research
                                      function                   and Development Command.
              Barometric altimeter
              PEEP capability
                                                                 References
              capability gap, which has just recently passed the digital pro-  1.  Eastridge BJ, Mabry RL, Seguin P, et al. Death on the battlefield
              totype manufacturing and patenting phase of development.   (2001–2011):  Implications  for  the  future  of  combat  casualty
                                                                    care. J Trauma Acute Care Surg. 2012;73(6 Suppl 5):431–437.
              However,  this  milestone  in  itself  should  not  be  unacknowl-  doi:10.1097/TA.0b013e3182755dcc
              edged, considering we can now begin to have a profession-wide   2.  Gerhardt RT, Strandenes G, Cap AP, et al. Remote damage con-
              discussion  regarding  future  advancements  in  this  uncharted   trol resuscitation and the Solstrand Conference: defining the need,
              territory of medical technology.                      the language, and a way forward. Transfusion. 2013;53(Suppl 1).
                                                                    doi:10.1111/trf.12030
              Future planned works include physical device prototyping and   3.  Mikhail J. The trauma triad of death: hypothermia, acidosis, and
              development of the STEAM device’s ability to heat and humid-  coagulopathy. AACN Clin Issues. 1999;10(1):85–94. http://www.
                                                                    ncbi.nlm.nih.gov/pubmed/10347389
              ify ambient air to physiologic levels, per industry standard. As   4.  Simmons JW, Powell MF. Acute traumatic coagulopathy: patho-
              research and development continues to device fabrication and   physiology and resuscitation. Br J Anaesth. 2016;117:iii31–iii43.
              testing, we will be able to standardize the STEAM for use in   doi:10.1093/bja/aew328
              future animal model studies. We estimate that the temperature   5.  Balvers K, van der Horst M, Graumans M, et al. Hypothermia as
              and humidity of ambient air will increase as it passes through   a predictor for mortality in trauma patients at admittance to the
              the STEAM device in proportion to the electrical power sup-  intensive care unit.  J Emerg Trauma Shock. 2016;9(3):97–102.
                                                                    doi:10.4103/0974-2700.185276
              plied to the heating and humidifier elements. A dose-response   6.  Joint Trauma System. Hypothermia Prevention, Monitoring, and
              curve and power draw can then be measured to determine if/  Management. Joint Trauma System Clinical Practice Guideline.
              what improvements to the design are necessary to meet perfor-  2012;(September):1–11.
              mance requirements.                                7.  Wang HE, Callaway CW, Peitzman  AB,  Tisherman SA. Admis-
                                                                    sion  hypothermia  and  outcome  after  major  trauma.  Crit Care
                                                                    Med. 2005;33(6):1296–1301. doi:10.1097/01.CCM.0000165965.
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                                                                 8.  Dickey NW. Combat trauma lessons learned from military opera-
              Although the future of battlefield medicine is unknown, it is   tions of 2001-2013. Published online 2015.
              predicted that PCC will become commonly practiced requir-  9.  Howard JT, Kotwal RS, Turner CA, et al. Use of combat casu-
              ing medical and technological innovation in prehospital care.   alty care data to assess the US military trauma system during the
              Currently there are medical capabilities that can only be de-  Afghanistan and Iraq conflicts, 2001–2017. JAMA Surg. 2019;
              livered in the hospital setting or in locations with more robust   78249(7):2001–2017. doi:10.1001/jamasurg.2019.0151
              resources. We estimate that hypothermia management requires   10.  Shackelford SA, del Junco DJ, Powell-Dunford N, et al. Associ-
                                                                    ation of prehospital blood product transfusion during medical
              innovation to better combat the lethal triad, especially in the   evacuation of combat casualties in Afghanistan with acute and
              PCC setting. We have identified such a capability gap – the   30-day survival. JAMA. 2017;318(16):1581–1591. doi:10.1001/
              current inability to heat and humidify inspiratory air of venti-  jama.2017.15097
              lated patients in the prehospital setting. Through STEAM, we   11.  Blackbourne LH, Baer DG, Eastridge BJ, et al. Military medi-
              can bring the above capability far forward into the most aus-  cal revolution: prehospital combat casualty care. J Trauma Acute
              tere environments. Thus, it can bring the in-hospital standard   Care Surg. 2012;73(6 Suppl 5):372–377. doi:10.1097/TA.0b013e
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              of care into the pre-hospital setting, likely reducing morbidity   12.  Kragh JF, Dubick MA, Aden JK, et al. U.S. military use of tourni-
              and mortality of the injured.                         quets from 2001 to 2010. Prehosp Emerg Care. 2015;19(2):184–
                                                                    190. doi:10.3109/10903127.2014.964892
              Author Contributions                               13.  Morrison  JJ,  Ross  JD,  Poon  H,  Midwinter  MJ,  Jansen  JO.
              BP  conceived  the  invention  concept  and  design. All  authors     Intra-operative correction of acidosis, coagulopathy and hypo-
              contributed to the evolution of the concept and design. BP re-  thermia in combat casualties with severe haemorrhagic shock.
                                                                    Anaesthesia. 2013;68(8):846–850. doi:10.1111/anae.12316
              fined and created the design as filed. BP, RS, and LT obtained   14.  Ditzel RM, Anderson JL, Eisenhart WJ, et al. A review of trans-
              funding. RS wrote the first draft, and all authors contributed,   fusion- and trauma-induced hypocalcemia: is it time to change
              edited, and approved the final manuscript.            the lethal triad to the lethal diamond? J Trauma Acute Care Surg.
                                                                    2020;88(3):434–439. doi:10.1097/TA.0000000000002570
              Disclosures                                        15.  Wray JP, Bridwell RE, Schauer SG, et al. The diamond of death:
              The views expressed are solely those of the authors and do   hypocalcemia  in  trauma  and  resuscitation.  Am  J  Emerg  Med.
                                                                    2021;41:104–109. doi:10.1016/j.ajem.2020.12.065
              not reflect the official policy or position of the Uniformed Ser-  16.  Friedman J, Ditzel RM, Fisher AD. Coagulopathy associated with
              vices University, US Army, Department of Defense, or the US   trauma: a rapid review for prehospital providers.  J Spec Oper
              Government.                                           Med. 2022;22(2):110. doi:10.55460/ul89-sc0z

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