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Goal of This Study                                 28,222 (72.8%) of those subjects. Within this dataset, there
              We seek to compare outcomes of casualties undergoing crico-  were 194 (0.7%) subjects who underwent cricothyrotomy
              thyrotomy versus supraglottic airway placement in the prehos-  versus 22 (0.1%) who underwent SGA placement as the sole
              pital, combat setting.                             documented means of airway intervention. Subjects in the
                                                                 cricothyrotomy group compared with the SGA group had a
                                                                 lower median age, similar sex distribution, similar affiliations,
              Methods
                                                                 similar mechanisms of injury, similar theaters of operations,
              Data Acquisition                                   and similar composite injury severity scores (ISSs) but less se-
              We identified subjects as part of a larger descriptive study of   vere scores for the thorax body region (Table 1). There was a
              ED interventions for trauma patients in Iraq and Afghanistan   trend toward worse AIS for the face region in the cricothyrot-
              using predefined search codes. This is a retrospective review of   omy group but a trend toward less severe scores for the abdo-
              prospectively collected data within the registry. We searched   men. Survival to hospital discharge rates were similar (Table
              our dataset for all subjects who had a documented supraglot-  1). When using a binary cutoff of AIS 3 or greater (serious)
              tic airway device or cricothyrotomy performed as the sole doc-  for the head, the cricothyrotomy group had a higher rate of
              umented airway intervention before reaching the emergency   serious head injuries (67.5%, n = 131 versus 45.5%, n = 10,
              department at a combat support hospital (CSH) or forward   p = .0393). When applying the same binary measurement
              surgical team (FST). We excluded subjects if they had more   to the face, we were unable to detect a significant difference
              than one airway intervention documented.           (4.6%, n = 9 versus 4.6%, n = 1, p = .984). When documented
                                                                 in the prehospital setting, median GCS scores were similar for
              The US Army Institute of Surgical Research regulatory office   the two groups (median 3 [IQR 3–6], n = 95 versus median 3
              reviewed protocol H-16-005 and determined it was exempt   [IQR 3–7.5], n = 20, p = .591). We also found no difference for
              from institutional review board oversight. We obtained only   emergency department arrival GCS (3 [3–5.5], n = 188 versus
              deidentified data.                                 3 [3–5.25], n = 21, p = .469).


              Department of Defense Trauma Registry Description  Regression Analyses
              The Department of Defense Trauma Registry (DoDTR), for-  On univariable analysis, the OR of survival was similar for
              merly known as the Joint Theater Trauma Registry (JTTR), is   SGA  versus  cricothyrotomy  (1.20,  95%  confidence  inter-
              the data repository for DoD trauma-related injuries. 12,13  The   val 0.49–2.94). We then performed a series of multivariable
              DoDTR includes documentation regarding demographics, inju-  analyses controlling for confounders comparing SGA versus
              ry-producing incidents, diagnoses, treatments, and outcomes of   cricothyrotomy. When controlling for injury scores by body
              injuries sustained by US/non-US military and US/non-US civilian   region, the OR was not significant (OR 1.14, 0.42–3.10).
              personnel in wartime and peacetime from the point of injury to   When controlling for the presence of a serious head injury
              final disposition. The DoDTR comprises all patients admitted to   (AISBR1 3 or greater, binary), the OR was not significant (OR
              a Role 3 (fixed-facility) or FST with an injury diagnosis using the   1.06, 0.43–2.65). No significant difference was noted when
              International Classification of Diseases, Ninth Revision (ICD-9)   controlling for the mechanism of injury (OR 1.12, 0.45–2.76),
              of 800 to 959.9, near-drowning/drowning with associated injury   patient category (OR 1.17, 0.47–2.90), or ED GCS (OR 1.64
              (ICD-9 994.1), or inhalational injury (ICD-9 987.9) and trauma   0.62–4.30).
              occurring within 72 hours from presentation. We defined the
              prehospital setting as any location before reaching an FST or a   Discussion
              CSH to include the Role 1 (point of injury, casualty collection
              point, battalion aid station) and Role 2 (temporary limited-ca-  We evaluated combat casualties undergoing either cricothy-
              pability forward-positioned hospital inside combat zone without   rotomy or SGA for advanced airway management in the pre-
              surgical support). The registry categorization scheme considers a   hospital setting. We found no difference in survival between
              Role 2+ (or variant with surgical support) to be the ED.  these two groups. This finding persisted on multiple regression
                                                                 analyses controlling for several factors, including injury scores
                                                                 by body region.
              Analysis
              We performed all statistical analyses using Microsoft Excel   Survival among patients undergoing either intervention
              (version 10; Redmond, WA) and JMP Statistical Discovery   (54.6% for cricothyrotomy and 59.1% for SGA) was higher
              from SAS (version 13; Cary, NC). We compared study vari-  than previously published data. Studies on military prehospital
              ables between subjects undergoing cricothyrotomy versus   airway interventions during the recent conflicts that reported
              SGA placement using a Student t test for continuous variables   mortality outcomes found a combined survival of 38.5% (15
              expressed as means with standard deviations, Wilcoxon rank   of 39) for cricothyrotomy and 7.1% (1 of 14) for SGA. 14–17
              sum test for ordinal variables expressed as medians and inter-  The higher survival in our study may reflect exclusion from
                               2
              quartile ranges, and  χ  test for nominal variables expressed   the DoDTR of casualties who died before arrival to an FST or
              as numbers and percentages. For binary outcomes, we used a   fixed-facility, whereas previous studies included those killed
              logistic regression analysis to report ORs.        in  action.  Likewise,  subjects  in  our study  may  have under-
                                                                 gone stabilization at a battalion aid station or higher echelon
                                                                 of care, whereas previous reports primarily analyzed casual-
              Results
                                                                 ties evacuated directly from the point-of-injury to an FST or
              Overall Analysis                                   fixed-facility. Additionally, our study captured more expo-
              During the study period, there were a total of 38,769 encoun-  sures by comparison: 194 versus 39 cricothyrotomies, and 22
              ters in the  DoDTR. Our predefined ED search codes captured   versus 14 SGAs. Our findings suggest clinically appropriate

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