Page 23 - Journal of Special Operations Medicine - Spring 2014
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Able to fight – Mobic and Tylenol, 2) Unable to fight   noted that OTFC works better than IM morphine and
              and  in  no risk  of  shock  –  OTFC  800mcg,  3) Unable   is often given in conjunction with IM morphine. SEAL
              to fight and in or at risk of shock – Ketamine 50mg   medics do not routinely carry ketamine. (Tarin Kowt
              IM. (BAF Role I – CJSOTF; BAF Role I – 1st Infantry   Role I – NSW)
              Division)
                 65. The weekly JTS trauma teleconferences on oc-  Recommendations for Military Research
              casion note that casualties who are given opioids are   and Development Commanders included:
              either in shock when the medication is administered or      3. As nausea and emesis can occur with opiate ad-
              become hypotensive subsequently. No studies have been   ministration, develop an oral transmucosal fentanyl ci-
              published from the current conflict that review out-  trate lozenge with ondansetron (“fentanyl-ondansetron
              comes in combat casualties as a function of the type and   swirl lollipop”).
              route of analgesia used in combat casualties as well as      4. Develop an oral transmucosal ketamine lozenge
              the type and severity of wounds sustained, and physio-  product (“ketamine lollipop”).
              logic parameters indicative of circulatory or respiratory      5. Similar to the IM auto-injector used for mor-
              status. (CoTCCC Chairman)                          phine, develop a ketamine 50mg IM auto-injector for
                 74. The USAF Pedro & Guardian Angel Team pri-   pre-hospital trauma care. Explore other potential routes
              marily provides Combat Search and Rescue (CSAR)    of ketamine administration to include intranasal and
              support and secondarily provides casualty evacuation   transcutaneous.
              (CASEVAC) support. . . . . Medical equipment includes      16. Conduct a retrospective study of combat casu-
              Propaq electronic monitors, Golden Hour boxes, 2 “D”   alty outcomes in the DoD Trauma Registry as a function
              cylinders of oxygen, blood components or Hextend (no   of the type and route of pre-hospital analgesia used as
              LR or NS); hypothermia prevention through Ranger   well as the type and severity of wounds sustained and
              Rescue Wrap (heavy sleeping bag, 360 degree access, ac-  physiologic parameters indicative of circulatory or re-
              tive heating pads) and wool blanket; they use ketamine   spiratory status.
              liberally and consider it the best option for analgesia in
              combat casualties. (Bastion Role I – USAF Pararescue)  Recommendations for the
                 88. There are meetings with USA MEDEVAC per-    U.S. Central Command included:
              sonnel and USAF CASEVAC personnel every other Fri-     10. Explore all options to enable intranasal ket-
              day … Both systems are using and like ketamine. There   amine for pre-hospital analgesia in combat casualties.” 5
              have been no known adverse effects from pre-hospital
              ketamine in the KAF AO. (KAF Role III – Intensivist)  Prehospital care reports from the point of injury are of-
                 202. The impact of pre-hospital opioid analgesia   ten lacking and, even when present, rarely include any
              on casualty outcomes has not been well-documented.   reports whatsoever of administration of analgesics prior
              (CoTCCC Chairman)                                  to aeromedical evacuation. The availability and admin-
                 204. There is a moral obligation to treat pain. Ef-  istration of analgesics in this phase of care is, for all
              fective analgesia also helps to decrease the risk of PTSD.   intents and purposes, unknown (Col Jeff Bailey, JTTS
              Opioids are overused at present. Ketamine is not re-  Director, personal communication, 2013).
              ally a new option, but there is relatively little ketamine
              use in theater at present. The use ratio of ketamine as   Morphine Sulfate
              compared to opioids is about 1:25. This ratio should   The narcotic most frequently used for prehospital anal-
              approximate 1:1. From 1mg to 3mg of midazolam is   gesia on the battlefield during the past century has been
              useful for ketamine side-effects. Ketamine should not   morphine.  After morphine was discovered in 1804, it
                                                                         17
              be given IV push, but injected over 1 minute. (Theater   was used liberally during the Civil War, resulting in such
              Trauma Conference – V Corps Command Surgeon)       a significant incidence of opioid dependency that this
                 205. TF Med A theater clinical operations has been   became known as the “Soldier’s disease.” During World
              tasked to obtain single dose vials of ketamine (currently   War  II,  morphine  use  was  associated  with  overdoses
              only available in very concentrated multi dose vials) and   and, in many cases, death. 6,10  Morphine has been the
              a ketamine auto-injector. (Theater Trauma Conference –   most widely used opioid analgesic because of its famil-
              TF Med A Commander)                                iarity and its simplicity. 18
                 238. There was unanimous agreement among the
              USMC/USN physicians and corpsmen interviewed that   Opioids are contraindicated in patients and casualties
              having a ketamine auto-injector would be a very desir-  with hypotension  but are still being given to casual-
                                                                                2–4
              able addition to battlefield analgesia options. (Bastion   ties who are either in hemorrhagic shock or who sub-
              Role I – USMC/USN physicians and corpsmen)         sequently become hypotensive.  No studies were found
                                                                                           5
                 253. Each SEAL Operator carries a morphine 10mg   during this review that examined the safety and efficacy
              IM auto-injector for battlefield analgesia. SEAL medics   of IM morphine use during the past 12 years of conflict



              Triple-Option Analgesia Plan for TCCC                                                           15
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