Page 304 - ATP-P 11th Ed

Pregnancy class: Generally considered to be safe
Side-effects/precautions:
• Extravasation may cause tissue damage and necrosis.
• Rapid injection may cause vasodilation, hypotension, bradycardia, cardiac dysrhythmia,
syncope, and cardiac arrest.
Other notes:
• Will precipitate if mixed with sodium bicarbonate.
TMEP use: Crush Injury Protocol
®
Ceftriaxone Sodium (Rocephin )
Aviation personnel are grounded for the initial 24 hours of antibiotic therapy and
until the medical condition no longer interferes with safely performing aviation duties and
the patient is free of side-effects.
Description: 3 generation cephalosporin
rd
SECTION 3 Indications: Serious infections of the lower respiratory tract (i.e., pneumonia); urinary tract;
• Broad-spectrum bactericidal antibiotic for IV/IM use
skin infections; intra-abdominal infections (especially penetrating abdominal trauma); pen-
e trating trauma to the extremities; and CNS infections
Adult dose: 1–2g IM/IV daily or in divided doses bid; max dose 4g/day
Pediatric dose: 50–75mg/kg given in divided doses q12hr; max dose 2g/day
K9 Dose: 1g IV/IM daily. May cause pain on IM injection. Give IV slowly over 30
minutes.
Contraindications:
• Use caution in patients with a history of:
° Penicillin allergy
° Hepatic dysfunction
° Liver dysfunction
Pregnancy Category B
Side-effects:
• Headaches
• Dizziness
• Nausea
• Vomiting
• Diarrhea
• Abdominal cramps
• Urticaria
• ↑ temperature
Adverse reactions:
• Eosinophilia

294 SECTION 3 RECOMMENDED DRUG LIST (RDL)