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for veno-arterial (VA) ECMO, but no training platforms have   and met inclusion criteria were used. The study comparison
          been developed for Role 2 surgical teams to offer VV ECMO   groups were data from the 12 participants before and after
          in operational environments or to provide sustainment of   the course.
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          knowledge and skills.  To close this training gap and provide
          increasingly available ECMO capabilities in a range of fu-  The study was conducted in accordance with the regulations
          ture conflict environments, a rapid and operationally relevant   and guidelines of the Animal Welfare Act, the National Insti-
          training course is required. We hypothesize that SOSTs can be   tutes of Health Guide for the Care and Use of Laboratory An-
          rapidly trained to safely and effectively cannulate and manage   imals, and the American Association for the Accreditation of
          VV ECMO patients. We also describe the use of a civilian-mil-  Laboratory Animal Care. The animals were housed at the 81st
          itary partnership to integrate operational military physicians   MDG CRL, where the study was conducted. The study was
          into a high-volume civilian ECMO center call schedule.  funded by a 711th Human Performance Wing (HPW) Studies
                                                             and Analysis (S&A) grant.
          Methods
                                                             ECMO Materials
          Study Design                                       The CARDIOHELP ECMO pump (Maquet Getinge Group
          We developed a prospective controlled study evaluating the   CARDIOHELP-I REF 70104-8012) and circuit (Maquet HLS
          efficacy of a VV ECMO training course for SOST personnel.   Set Advanced 7.0, HLS 7050 USA, 701052794) were used.
          This study was reviewed by the University of Maryland and   Cannulation was performed using Maquet 19-French venous
          81st Medical Group (81st MDG) Institutional Review Boards   cannulas (PVS 1938) and Medtronic Bio-Medicus 19-French
          and approved as exempt. In addition, this study was approved   venous cannulas (96670-019).
          by the 81st MDG Clinical Research Laboratory (CRL) Institu-
          tional Animal Care and Use Committee (IACUC).      Course Materials
                                                             Educational materials were developed by subject matter ex-
          Primary and Secondary Aims                         perts (SMEs) at the R Adams Cowley Shock Trauma Center
          Our primary aim was to determine  whether SOST  person-  (STC) at the University of Maryland Medical Center (UMMC),
          nel could be rapidly trained to safely and effectively cannu-  a high-volume ECMO institution. The STC has a quarterly
          late  and  manage  for VV  ECMO  in  conditions  that  may  be   ECMO training course designed for physicians, advanced
          encountered (white light and low light). Rapid training was   practice providers, and nurses.  This course was adapted to
          defined as completion of the 2.5-day course. Previous studies   include relevant operational topics. Lectures included:  VV
          on “rapid” courses on VV ECMO cannulation and its man-  ECMO physiology, management, cannulation techniques and
          agement involved training that had been completed in 3 days   cannula selection, setting up the circuit, managing the circuit,
          or less. 17,18  “Safe and effective” cannulation was defined as   managing complications, indications and contraindications,
          successful set-up of the circuit and cannulation during the val-  and care of the patient during cannulation and while on VV
          idation phase without technical complication. Technical com-  ECMO. Skills stations with hands-on and mannequin train-
          plications were determined by 2 independent, expert reviewers   ing were developed by civilian and military ECMO SMEs, and
          with ECMO cannulation credentials and clinical experience   Center for the Sustainment of Trauma and Readiness Skills
          in the procedure and management who applied standards of   (C-STARS-Baltimore)  cadre  with  expertise  in  ECMO.  Skills
          care and clinical competence to the validation phase of train-  station topics included: assembly of the ECMO circuit, bifem-
          ing. Criteria included: priming and setting up the circuit, ob-  oral cannulation for VV ECMO, Role 2 VV ECMO case, and
          taining ultrasound guidance, placement of cannulas, assessing   managing  complications.  Performance  at  each  skills  station
          placement of cannulas through ultrasound and measurement,   took place with white lights on and in darkness. White light
          connection of the cannulas to the ECMO circuit, initiating   training simulated a hospital environment, and the procedures
          VV ECMO, removing air from the circuit, simulated cannula   performed in darkness were undertaken with headlamps (Fig-
          dislodgement, titration of the circuit, and performance of   ure 1). Step-by-step instructions were provided to all partic-
          procedures and surgeries. These competencies were based on   ipants: (1) bifemoral cannulation from an expert consensus
          previous, established ECMO training. 18,19         survey performed prior to the course (Supplemental Table 1)
                                                             and (2) Maquet Cardiohelp-I set-up and priming instruction
          Our secondary aim was to determine whether SOSTs could   sheet. The course was divided into two phases: (1) didactic
          then perform surgical and resuscitative procedures in under   (training) phase and (2) validation (testing) phase (Supplemen-
          2 hours on VV ECMO patients given that trauma patients   tal Figure 1).
          requiring VV ECMO commonly require other procedures in
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          a time-sensitive manner.  Participants’ confidence and knowl-  Didactic (Training) Phase
          edge were evaluated with a self-assessment and a multi-choice   The didactic course phase took place at the STC simulation
          knowledge questionnaire immediately before and after the VV   center. In addition to the previously mentioned lecture and
          ECMO training course. Pre-course participant demographics   skills station topics listed, participants completed pre-course
          were obtained through anonymous surveys.           self- assessments (23 questions) rating their degree of confi-
                                                             dence with cognitive (9 questions), technical (11 questions),
          Study Setting and Population                       and behavioral (3 questions) aspects of VV ECMO on a 5-point
          Volunteers from Detachment 1 and Detachment 2, 720th Op-  Likert scale. 20–22  This self-assessment was adapted from a pre-
          erational Support Squadron (OSS/SOST) were solicited via   viously published survey.  Since this was a validation study,
                                                                                 23
          email. Personnel eligible for inclusion were (1) qualified SOST   there was no absolute cutoff for adequacy of confidence im-
          personnel who (2) had no previous formal ECMO training. Al-  provement. Our goal was to demonstrate how our course im-
          ternative qualified SOST Air Force Specialty Code personnel   proved participants’ confidence. Participants also completed a
          (AFSCs) that are acceptable substitutes for team composition   pre- and post-course 25-question multiple-choice knowledge

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