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Medical


                                 SEIZURE

                        Signs and Symptoms:   Differential Diagnosis:
                      •  Decreased Mental Status  •  CNS Trauma
                      •  Seizure Activity  •  Tumor/Mass/Infection
                      •  Somnolence      •  Metabolic
                      •  Incontinence    •  Hypoxia
                      •  Evidence of Trauma  •  Electrolyte Abnormality
                      •  Loss of Consciousness  •  Drugs/Toxins
                      •  Oral Injuries (e.g., Tongue,  •  Alcohol/Benzodiazepine Withdrawal
                        Buccal)          •  Stroke
                                         •  Eclampsia
                                         •  Hyperthermia
                                         •  Hypoglycemia
                                 Universal Patient Care Guideline   LORAZEPAM  2-4mg IV/IM
               Continued from:      O2 (if Hypoxemic)        OR
            Tactical Evacuation Guideline   IV / IO Guideline
                                    Cardiac Monitor
                                Patient Safety (ensure secured to litter)   MIDAZOLAM
                                                        5mg IV/IO/IN or 10mg IM/IN
              50% Dextrose 25g IV   YES   Blood Glucose <60 0?   May Repeat Anticonvulsants 2x q3-5min
                                         NO, Postictal   (Must Have Definitive Airway Control)
                                                        AIRWAY Guideline for RSI
                     OR            Having Active Seizure?   YES

              Glucagon 1mg IV/IM
                                         NO
                             NO  Evidence of Significant Trauma?   Status Epilepticus:
         NO    Glucose 60-250?           YES         Keppra 40-60mg/kg over (max 4500mg) IV
                                                           over 15min
                                  SPINAL IMMOBILIZATION
                    YES               GUIDELINE
                                                           Consider:
              Recurrence of Seizure?   NO             Pregnancy (Obstetric Emergency) Mag
                                Consider: HEAD INJURY Guideline   Sulfate 4g IV o over 15min Monitor for
                    YES                                    Hypotension
              Restart Guideline at:
                                               i
                                              m
                                             5
                                            q
                                             1
              Having Active Seizure?   Monitor and Reassess q15min  n  Consider: AIRWAY Guideline
                                  When appropriate, return to:
                                 Tactical Evacuation Guideline   Consider Elevated ICP
                                                       HEAD INJURY Guideline
          Pearls:
          •  Status epilepticus defined as seizure >15min or two or more continuous seizures without a period of
            consciousness/recovery. This is a real emergency requiring rapid airway control, treatment, and transport to the
            nearest suitable medical treatment facility.
          •  Paralysis for airway control does not stop seizure activity–only hides it. A seizure is a CNS electrical
            phenomenon and damage is still being done even when no muscular activity seen due to paralysis.
          •  Anticipate further seizure activity/recurrence and monitor continually.
          •  Assess probability of toxin, occult trauma, abuse, or substance use.
          •  Be prepared to assist with ventilations with the use of midazolam. If airway controlled and ventilating well – may
            give total of 4 doses of midazolam.
          •  In pregnant patients, magnesium should be first line to abort non-epileptic seizures. Midazolam should
            only be used if this fails (pregnancy class D).
          •  Adult alcohol withdrawal or malnutrition (Thiamine 100mg IV)
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