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the importance of accurate infusions, most U.S. Army medics   generator (Research Randomizer, https://www.randomizer.org)
          returning from deployment identified medication administra-  to decide whether they performed infusion testing with the
          tion as an essential skill, but also stated that they would have   TM or DripAssist device first. Each volunteer participated in
          benefitted from additional training prior to deployment. 9  an isolated environment with a standardized set-up for each
                                                             infusion rate tested (Figure 3). Volunteers were allotted five
          The DripAssist (Shift Labs, Seattle, WA) is a small 3.8-ounce,   minutes to familiarize themselves with the DripAssist prior to
          battery-powered, in-line device that monitors the infusion rate   testing. They were then asked to achieve infusions at rates of
          of an IV medication, providing a user interface that displaces   250mL/hr and 125mL/hr based on prior literature, as well as
                                         10
          the rate and volume infused (Figure 2).  Medics are still re-  40mL/hr based on recommended sedation rates for PCC. 10,12
          quired to manipulate the rate via the roller clamp, however the
          DripAssist device calculates the infusion rate for them, thereby
          eliminating much of the calculations required in the TM. Lim-
          ited research demonstrates that non-physician medical provid-
          ers find the use of the DripAssist to be easier for infusion rate
          manipulation than the TM, but provides no direct comparison
          for  device  impact  on  time  to  achieve  infusion  rates  or  drip
                     10
          rate accuracy.  A single case report published the use of the
          DripAssist in an austere setting to manage infusion rates in
          a casualty in Syria. There was a perceived benefit among the                            FIGURE 3
          medical team, however no quantitative data compared infu-                               Standardized
                                                                                                  testing set-up.
          sion rates to other methods. 11
          FIGURE 2  DripAssist device features.








                                                             Time began when volunteers were handed the prescribed rate
                                                             and stopped when the participant stated they had established
                                                             the required rate. Once volunteers verbalized the established
                                                             rate, a single investigator counted the number of drops in the
                                                             drip chamber over 30 seconds and then doubled the number
                                                             counted to evaluate for rate accuracy. We defined accuracy as
                                                             within ten percent based on prior studies of infusion rate ac-
                                                             curacy. 6,13  Once volunteers completed three infusions for their
                                                             initial method, they proceeded to their second method type.
          We sought to directly compare the DripAssist to the TM for   Upon  completion  of both  methods,  volunteers completed  a
          time to achieve infusion rates, infusion rate accuracy, and end   post-participation survey.
          user feedback amongst U.S. Army medics.
                                                             Continuous variables, including time, rate accuracy, volume
                                                             accuracy, and user confidence, were analyzed using a Mann-
          Methods
                                                             Whitney U test, while ordinal data of user appraisal was ana-
          The Regional Health Command – Pacific Institutional Review   lyzed using a Wilcoxon Signed-Rank test. Demographic data
          Board determined protocol #221047 exempt from board re-  was evaluated using Microsoft Excel (Microsoft, https://www
          view.  We conducted a prospective, randomized, crossover   .microsoft.com/en-us/microsoft-365/excel), while all other data
          study utilizing a convenience sample of active-duty U.S. Army   was analyzed with SPSS statistical software (IBM, https://www
          medics stationed at Joint Base Lewis-McChord, Washington.   .ibm.com/spss).
          Volunteers were excluded if they self-reported any prior for-
          mal advanced medical training, such as medical school, Special   Results
          Operations Combat Medic, paramedic, physician assistant, li-
          censed practice nurse, registered nurse, or if they had any phys-  A total of 22 U.S. Army medics initially volunteered for study
          ical limitations that would prevent them from participation.  participation, however one was excluded due to prior advanced
                                                             training, and one withdrew due to scheduling conflicts. The
          Given a dearth of literature, investigators agreed upon a mean   resulting 20 medics completed 120 total infusions over three
          clinically important difference (MCID) of 60 seconds between   days of testing at a single outpatient clinic. Median volunteer
          modalities for achieving infusion rates. Utilizing a cross-  age was 22 years old; most were in the rank of E-4 (65%) and
          over design, a power analysis established a sample size of 20   most participants were male (85%, Table 1). Four volunteers
          volunteers.                                        (20%) reported never having established a rate-specific infu-
                                                             sion in a live patient with the TM. Of those who reported IV
          Volunteers received a brief introduction to the study, then com-  infusion experience, 65% reported performing between one
          pleted a demographic survey, including prior IV infusion ex-  and five infusions prior to the study, with smaller amounts
          perience. They then were randomized using a random number   reporting more. One volunteer (5%) reported experience with

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