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collapse.”  Van Roekens et al.  also described external aor-  victim, and by lowering the patient from waist height to floor
                  26
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          tic compression in a case of tetralogy of Fallot cyanotic crisis.   height so rescuers are atop victims and can lock their arms.
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          This involved clinicians applying digital PEAC along with an   With these strategies, and with maximal effort, participants
          improvised abdominal tourniquet (i.e., a circumferentially ap-  could manually compress almost 70% of their body weight
          plied blood pressure cuff). The treatment was associated with   for approximately 2 minutes. Using a single knee, participants
          an increase in arterial oxygen saturation from 19% to 35%.    compressed approximately 80% of their body weight and
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          Used as a temporizing measure, Van Roekens suggest “external   could maintain the maximal effort for as long as 20 minutes.
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          manual compression of the abdominal aorta can be as effective   In short, we have demonstrated that using two hands or a knee
          as surgical clamping or vasopressors” and can garner valuable   is worthwhile when there is no alternative. However, our am-
          time to bridge patients to definitive surgical repair. 36  balance studies  have demonstrated why a device or invasive
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                                                             intervention should decrease the likelihood of exsanguination
          Trauma                                             during transfer. In other words, it is not a case of PEAC or a
          PEAC after trauma was reportedly taught to tactical provid-  device, but rather PEAC until a device can be reliably applied,
          ers in the 1990s to temporize inguinal hemorrhage.  However,   especially if providers are to remain with their seat belt on
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          the first written description may be a 1983 article in Polish   during ambulance or helicopter transfer. 33
          on first aid hemorrhage control (Figure 2).  The first, written,
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          English-language recommendation for trauma appears to be   Recently, we  confirmed  using  ultrasound  that  rescuers  with
          from retired consultant general surgeon Harry Espiner, in The   minimal training could rapidly arrest femoral artery blood
          Guardian newspaper. He suggested two fists, one placed above   flow  using  bimanual  PEAC.   Moreover,  we  showed  that
                                                                                    16
          and one below penetrating abdominal wounds to control hem-  PEAC could stop femoral blood flow within 20 seconds, albeit
          orrhage.  Our team (Douma et al.) described a peer-reviewed   in healthy volunteers.  Although our participants tolerated
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                30
          case report of PEAC application for a trauma patient in 2013.    the compression (median pain score on a 0–10 scale: 5; range,
                                                         15
          In that case, PEAC resulted in returned consciousness of a   4–7), Soltan et al.  have reported greater pain in obese women
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          moribund victim of multiple GSWs to the abdomen pelvic and   and a increased pain and compression failure were reported
          lower limb. Notably, a heavier rescuer (>90kg) arrested bleed-  in a junctional tourniquet trial in a participant with above-
          ing, resulting in the patient regaining consciousness. Transfer of   average body mass. 36
          care to a lighter rescuer, as well as ambulance transfer, resulted
          in ineffective PEAC, clinical deterioration, and, ultimately,   From a practicality standpoint, we are pleased to report we
          death.  An additional series of four illustrative cases have been   have taught PEAC to more than 200 clinicians and 80 other
               15
          recently published by Dr Bruce Paix et al. from Australia.    course participants. Training is free, reliable (using instructor
                                                         31
          Furthermore, a clinical team from Montreal has demonstrated   demonstration and student return demonstration), requires
          the use of an ultrasound probe to identify the aorta, compress   no equipment and takes less than 5 minutes. Moreover, reme-
          it, and confirm that compression was effective. 32  dial instruction is infrequently required because the bimanual
                                                             technique approximates that used for cardiac chest compres-
          FIGURE 2  External aortic compression.             sions.  Figure 3 outlines how PEAC could be integrated into
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          Early description of bimanual external compression of the
          “abdominal artery.” Adapted from Badowski and Zaras. 29  a chain of survival for life-threatening abdominal-pelvic and
                                                             junctional hemorrhage (Figure 3). 34
                                                             FIGURE 3  Life-threatening abdominal-pelvic and junctional
                                                             hemorrhage chain-of-survival.
                                                             Proposed “chain of survival” for life-threatening abdominal-pelvic
                                                             and junctional hemorrhage. Adapted from Douma et al. 34











                                                             Proposed Role and Rationale for PEAC in Trauma
                                                             Tactical Combat Casualty Care proposes a “platinum ten min-
                                                             utes”  to highlight the importance of early temporizing con-
                                                                 38
          Feasibility Studies                                trol of massive hemorrhage. Recent work argues for a shorter
          Our 2013 case led to a comprehensive research program,   3-minute window.  After all, blood flow from a single femoral
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          including feasibility,  technique optimization,  application   artery approximates 3L/min during stress.  Like us, Tjardes
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                          30
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          during  transfer,   and  ultrasound  assessment  in  healthy  vol-  and Luecking  challenge whether a device can be reliably re-
                      34
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          unteers.  We found that (perhaps intuitively) heavier rescuers   trieved and applied in that brief time. In contrast, manual or
                16
          compress more weight and that compression efficiency is in-  genicular PEAC can be applied immediately. Junctional tour-
          creased by optimizing technique. Specifically, we found that   niquet application conservatively takes longer than a minute.
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          one-handed compression resulted in the transmission of less   Use of REBOA in Zone 3 trauma (i.e., the area extending dis-
          than 30% of the rescuer’s body weight. Compression efficiency   tally from the lowest renal artery to the aortic bifurcation) is
          is increased with a second hand, a hard surface beneath the   promising, especially because it occludes femoral vessels via an
          112  |  JSOM   Volume 20, Edition 2 / Summer 2020
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