Page 161 - 2026 SMOG

PLASMALYTE A
Class
• Isotonic crystalloid solution
Mechanism of Action
• Replaces water and electrolytes.
Indications
• Hypovolemic shock; compatible with blood or blood components. It may be administered
before or following the infusion of blood through the same administration set (i.e., as a priming
solution), added to or infused concurrently with blood components, or used as a diluent in the
transfusion of packed erythrocytes.
Contraindications
• Use with caution for intravascular volume replacement for hemorrhagic shock due to
hemodilution and exacerbation of coagulopathy. Use with caution in patients with known
congestive heart failure and kidney disease. Excess administration may result in metabolic
alkalosis. Adverse Reactions: Rare
Drug Interactions
• Few in the pre-hospital emergency setting.
Dosage and Administration
• Hypovolemic shock; titrate according to the patient’s physiological response.
(See appropriate Protocols)

2026 Standard Medical Operating Guidelines (SMOG) • 153