Page 3 - JSOM Fall 2022
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from the

              PUBLISHER
              Michelle DuGuay Landers, MBA, BSN, RN
              Lt Col (Ret)


              Greetings JSOM Subscribers,                        TABLE 1  Medications Recommended in the TCCC Pain and Analgesia Guidelines  Contraindications  Side Effects
                                                                 Medication
                                                                                     Action(s)
                                                                            Dose(s)
                                                                 Acetaminophen   Two 500mg tablets   Antipyretic, analgesic via  Liver failure patients, unable   No major side effects
                                                                 (Paracetamol, Tylenol) (1000mg total) by mouth  unknown mechanism  to tolerate PO medication,
                                     The cover art for the Fall Edi­  Meloxicam (Mobic)  every 8 h  NSAID  known allergy  Increased bleeding
                                                                                           Renal injury/failure, severe
                                                                         15mg tablet by mouth
                                                                         24 h              life-threatening bleeding,
                                     tion of the JSOM is an illustra­                      unable to tolerate PO, known
                                                                                           allergy
                                     tion  capturing the  care  and   Fentanyl OTFC*  800μg transmucosal,   Opiate mu-agonist,   Significant facial wounds,   Increased altered mental
                                                                         repeat × 1 in 15 min if
                                                                                           hemodynamic instability,
                                                                                  OTFC dose made to
                                                                                                      status, respiratory
                                     teamwork associated with casu­      pain is uncontrolled  drop from casualty’s   opioid allergy, significantly   depression, potential drop in
                                                                                                      hemodynamic status
                                                                                  mouth when altered
                                                                                           altered mental status
                                     alty treatment and evacuation.   Fentanyl*   50μg (0.5–1μg/kg) IV/IO   Opiate mu-agonist,   Hemodynamic instability,   Increased altered mental
                                                                                  redistributes in adipose
                                                                                           opioid allergy, significantly
                                                                                                      status, respiratory
                                                                         or
                                                                         100μg  IN; repeat every   tissue and multiple   altered mental status  depression, potential drop in
                                                                                                      hemodynamic status
                                     The scene depicts a night time
                                                                                  doses can “stack” with
         Michelle D. Landers, Lt Col (Ret)                               30 min as needed  increased effect/side
                                                                                  effects
                                     TACEVAC with a UH60 Black­  Ketamine*  20–30mg (0.2–0.3mg/kg)  NMDA and glutamate   History of laryngospasm,   Nausea, vomiting, diplopia,
                                                                 (ANALGESIA)  slow IV/IO, repeat every   receptor antagonist,   prior ketamine   drowsiness, dysphoria,
                                     hawk being guided in by an          20 min as needed  dissociative anesthetic,   hypersensitivity or allergy,   confusion, emergence
                                                                                                      reactions, increased
                                                                                  partial opiate mu agonist  schizophrenia or active
                                                                         or
                                       Operator signaling with a chem­   50–100mg (0.5–1mg/kg)   psychosis   secretions, laryngospasm,
                                                                                                      tachycardia, increased blood
                                                                         IM/IN, repeat every 20–
                                                                                                      pressure, enhanced skeletal
                                     light. Meanwhile, an Operator       30 min, as needed            muscle tone
                                                                 Ketamine Infusion*   Initial dose: 1–2mg/kg   Same as above  Same as above  Same as above, though
                                     pulls security from the Humvee   (SEDATION)  slow IV/IO until    slower RATE of
                                                                         dissociation
                                                                                                      administration has been
                                     used to transport the casualty      then                         shown to decrease many side
                                                                                                      effects
                                                                         Maintenance: 0.3mg/kg
                                     and two medics to the rendez­       in 100mL 0.9% NS over
                                                                         5–15 min, repeat every
                                                                         45 min as needed
                                     vous site. The medics are per­  *Providers should have appropriate reversal agents (naloxone for all opioids) as well as all components of MSMAID to address any negative side
                                                                 effects of these medications.
              forming final reassessments while the Blackhawk is arriving.   IN = intranasal; IO = intraosseous; IV = intravenous; MSMAID = monitor, suction, machine [ventilatory support], airway, IV/IO, drugs;
                                                                 NMDA = N-methyl-d-aspartate; NS = normal saline; NSAID = nonsteroidal anti-inflammatory drug; OTFC = oral transmucosal fentanyl citrate;
                                                                 PO = by mouth; TCCC = Tactical Combat Casualty Care.
              The story shown is one of heroism and extreme competence, as
              each warfighter performs their role with excellence — a story   TABLE 3  Sedation Alternatives When TCCC Care Cannot Be Met and Environment Allows
                                                                                       SEDATIVES
              that has played out countless times through the recent decades   Medication  Dose  Action(s)  Contraindication(s)  Side-Effects
              of military deployment.                            Benzodiazepine*   Dosage varies as well   GABA agonist:   Renal or hepatic   Respiratory depression, depressed
                                                                                                   mental status, hypotension,
                                                                 (diazepam, midazolam,  as duration of action;
                                                                                   anxiolytic,
                                                                                          impairment, elderly or
                                                                 lorazepam,   lorazepam, midazolam,   sedative, muscle   critically ill patients,   paradoxical reactions, tachyphylaxis
                                                                 alprazolam,   diazepam most used   relaxant,   delirious patients,   (drug tolerance)
                                                                 clonazepam, etc.)  sedatives in drip form  anticonvulsant,   substance abuse
              Commemoration of Women’s History Month             Etomidate   0.1–0.3mg/kg IV for one   amnesic  Adrenal suppression,   Myoclonus, adrenal suppression,
                                                                                   GABA agonist,
                                                                         time dose; no longer   general anesthetic,  critical illness,   nausea, apnea
              We commemorate Women’s History Month (March 2022).         recommended for sedation  sedative hypnotic   requirement for
                                                                                          prolonged sedation
                                                                         due to adrenal suppression
              “Women in US Military History,” by Gretchen Garceau-Kragh,   Propofol*   0.5–2mg/kg IV initial dose;  GABA agonist,   Hypertriglyceridemia,   Bradycardia, QT interval
                                                                                   general anesthetic
                                                                         5–60μg/kg per min in
                                                                                          bradycardia,
                                                                                                   prolongation, profound hypotension,
                                                                                          hypotension, severe TBI
                                                                         prolonged sedation
                                                                                                   propofol infusion syndrome
              RP, MEd, MBA,  highlights the many accomplishments of   Dexmedetomidine   1μg /kg  IV  over  10  min  Alpha-2 adrenergic  Cardiac injury, existing   Hypotension, bradycardia,

                                                                         followed by 0.2–1.5μg      /kg/h  agonist
                                                                                          bradycardia, hypotension tachyphylaxis (drug tolerance),
                                                                 (Precedex)
              women in US military history. In addition, we would like to   Anesthetic Gases*   infusion for sedation   Mechanism   Vary to include lack of   Malignant hyperthermia, nausea and
                                                                         Dosage varies as well as
              recognize the following women lead authors in this edition:   (nitrous oxide,   duration of action  remains mostly   appropriate monitoring   vomiting, carbon monoxide poisoning
                                                                                   unknown
                                                                 halothane, isoflurane,
                                                                                          devices, those with severe
                                                                                          asthma, hepatic failure,
                                                                 desflurane,
                                                                 sevoflurane)             renal dysfunction, heart
              Roselyn W. Clemente Fuentes, MD (“Operation Blood Rain                      failure
                                                                 *Patients must have a protected airway when receiving these medications for deep sedation.
              Phase 2: Evaluating the Effect of Airdrop on Fresh and   GABA = gamma-aminobutyric acid; IV = intravenous; TBI = traumatic brain injury.
              Stored Whole Blood”),  Susan Modi, FNP  (“Development
              and Evolution of a Comprehensive Mild Traumatic Brain Injury   Fall Podcast
              Inpatient  Rehabilitation  Program: A Nursing Perspective”);   Articles being reviewed by the Podcast Team are:
              Nikki E. Barczak-Scarboro, PhD  (“Active Warfighter Resil-
              ience: A Descriptive Analysis” and “Active Warfighter Mental   Operation Blood Rain Phase 2: Evaluating the Effect of Airdrop
              Health Lower in Mid-Career”), and  Marie Hindorf, CRNA,   on Fresh and Stored Whole Blood by  Roselyn W. Clemente
              MSc (“Workload of Swedish Special Forces Operators Expe-  Fuentes, et al. (p. 9)
              rienced During Stressful Simulation Training: A Pilot Study”).   Active  Warfighter  Resilience:  A  Descriptive  Analysis  by
                                                                 Nikki E. Barczak-Scarborov, et al. (p. 22)
                                                                 Women in US Military History  by  Gretchen Garceau-Kragh
              Summer Edition Chart Correction
                                                                 (p. 75)
              We have a significant change regarding an article in the Sum­
              mer 2022 Edition of the JSOM. A dosage misprint appears   Our author interview will be with  Roselyn Fuentes, Lt Col,
              in the paper titled, “Analgesia and Sedation in the Prehospi­  USAF,  MC,  FS  (“Operation  Blood  Rain  Phase  2:  Evaluating
              tal Setting: A Critical Care Viewpoint” by Taylor DesRosier,    the Effect of Airdrop on Fresh and Stored Whole Blood”). Lt
              et al.                                             Col Fuentes is an associate professor of family medicine (MD,
                                                                 FAAFP, FAWM, MMAS), a flight medicine medical director/
              Several dosages in Tables 1 and 3 on pages 50 and 52 of the   flight medicine flight CC, and 96 MDG director of clinical
              Summer JSOM are listed as milligrams (mg) but should be mi-  research, Eglin AFB, FL.
              crograms (µg). Both charts were corrected and sent to all our   Our guest medic editor this quarter is Eric Dodson
              subscribers via direct emails and posted on all our social media   HM1(FMF/EXW), a former Corpsman with NSW,
              platforms in our 1 July newsletter (https://conta.cc/3R6DYtD).   who is reviewing “Active Warfighter Resilience: A
              Below are the two corrected tables.                         Descriptive Analysis.”
                                                                 We would love your feedback.
                                                                 Please email Podcasts@JSOMonline.org.
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