Page 54 - JSOM Summer 2020
P. 54

Antivenom Algorithm:
                                               CENTCOM AOR                                  NOTE:
                                                                                     Yellow background indicates that
                                                                                    a product meets both criteria below:
                                                                                    1) broad-spectrum regional coverage
                                             Follow list of steps outlined in CPG:    2) freeze-dried / field-stable
                                             Universal Approach to Snakebite
                                          Assessment, Diagnosis, and Treatment



                                                      Patient              Monitor for 24 hours and
                                                    with S/Sx of    NO     discharge according to
                                                    envenomation?               Step #17

                                                       Yes


                                CENTCOM AOR                                   CENTRAL ASIA
                                                     Region?
                              (except Central Asia)                               ONLY


                                                                      NO       Snake ID known?



                                                                                      YES



                                                                                       Confirmed
                                                     Syndrome?            NO     Gloydius halys or other Gloydius
                                                                                      species? (rare)


                                                                                         YES
                                       NEUROTOXIC   HEMOTOXIC  CYTOTOXIC
                                                                                     1st line = SIOBP-G
                                                                                 Gloydius halys or related Gloydius
                                                                                       species only!
                  1st line = POLYSERP-M                                             Initial dose = 2 vials,
              COMPLETE REGIONAL COVERAGE                                          additional 2 vials as needed
                                           YES      POLYSERP-M
                                                     available?
                    Initial dose = 6 vials,
                 additional 2 vials as needed
                                                       NO


                            MIDDLE EAST /
                                                     Region?          ARABIAN PENINSULA
                            CENTRAL ASIA


                                                                          NAVPC-P     YES
                                                                          available?
                              RAZI-P
                              available?
                                                                                     2nd line = NAVPC-P
                                                                                     Moderate coverage for
                                                                                 NEURO / HEMO / CYTO syndromes
                    YES
                                         NO                        NO          Initial dose varies by syndrome, see below

                                                                                             2nd line = NAVPC-P
                2nd line = RAZI-P                                        2nd line = NAVPC-P
                                    Contact snakebite  Contact snakebite                   Initial dose hemotoxic and/or
                Initial dose = 10 vials,                              Initial dose neurotoxic = 10 vials,  cytotoxic = 10 vials,
              additional 2 vials as needed  expert for consult  expert for consult  additional 5 vials as needed
                                                                                           additional 5 vials as needed




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