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an attempt to appreciate bleeding cessation. At 20 min-  This case study demonstrated that a motivated and in-
              utes after the arteriotomy, active bleeding was difficult   telligent, but untrained, first responder could successfully
              to visualize on ultrasound, and at 27 minutes after the   localize the actual anatomic site of an exsanguinating
              arteriotomy, bleeding appeared to have stopped. While   bleed and then could relatively easily compress this site to
              bleeding was appreciated on ultrasound subjectively, the   control the bleeding site using ultrasound-guided manual-
              hematoma size did not change substantially over the   compression techniques. This approach might comprise
              course of the procedure, leading to the understanding   a potential treatment algorithm for using UGMC tech-
              that the bleeding decreased over time before stopping   niques with novice users. In such an approach, a rapidly
              and did not continue uncontrolled for 27 minutes. Fol-  hemostatic device such as the iTClamp is used to quickly
              lowing bleeding cessation, attempts were made to ap-  control major vascular injury by creating an acute false
              preciate proximal and distal flow in the injured limb.   or pseudoaneurysm. This quickly contains blood loss but
              While proximal arterial flow was captured, potentially   retains mobility and independence of the casualty. De-
              indicating lack of thrombosis in the artery itself, distal   pending on the environment, such treatment might be de-
              flow could not be appreciated. At 57 minutes after the   finitive. However, if the environment and logistics permit,
              arteriotomy, the iTClamp was removed from the wound   with RMTUS, the actual anatomic site of extravasation
              and we were able to visually observe that the bleeding   could be definitively localized and compressed to acceler-
              had stopped and a clot had formed exterior to the artery   ate the natural processes of hemostasis.
              itself.
                                                                 With the greater availability of portable ultrasound, this
                                                                 might constitute a mentored technique that could be used
              Discussion
                                                                 early after wounding/injury in an environment where
              Efforts are under way in both civilian and military care   there is a provider, an ultrasound device, and Internet
              to improve hemorrhage control for all injuries, recog-  connectivity. Traditional standard-of-care packing, how-
              nizing that this offers the greatest chance of prevent-  ever, would not permit such an approach, as gauze pack-
              ing unnecessary postinjury death. Thus, improvements   ing would introduce an air-containing impediment with
              in techniques, systems applications, and even pharma-  very high acoustic impedance to the wound, which would
              cology have led to improved hemorrhage control and/  preclude meaningful ultrasound imaging.
              or outcomes. 22–24  However, the inability to treat junc-
              tional hemorrhage with standard tourniquets has been   It should be emphasized that RMTUS guidance is not
              identified as a capability gap by the US military. 25,26  In   required for the iTClamp to be efficacious but is merely
              response  to this challenge, the  Combat Ready Clamp   a potential technical adjunct. First responders in emer-
              (CRoC; Combat Medical; http://combatmedicalsystems.  gent situations need to be able to deal with hemorrhage
              com) was developed  to exert mechanical pressure  di-  control without outside direction, particularly noting the
              rectly over a wound or indirectly over the groin to arrest   challenges of establishing wireless connections and tele-
              hemorrhage.  In vivo studies have demonstrated effec-  mentorship in unstable environments. The iTClamp has
                        25
              tiveness of this device, although the application required   demonstrated the ability to not only stop the external
              1 to 2 minutes in ideal conditions and the application   egress of blood from a wound but also to stop the bleeding
              of compression pressures of 800–900mmHg, which in-  and ultimately form a clot, which may offer advantages
              duced complete ischemia of the proximal external and   over the CRoC and other hemorrhage-control devices
              internal iliac arteries, effectively blocking all collateral   in terms of quicker initial application, less pressure ap-
              circulation in the swine leg.  Thus, while effective in a   plication required, possible preservation of collateral limb
                                      25
              laboratory setting, there remain uncertainties about its   flow, and the ability to take the required skill out of the
              practical application in fully operational settings.  skill set of hemorrhage control. Further evaluations, espe-
                                                                 cially including comparative studies, are thus warranted.
              Portable, hand-carried ultrasound devices are another
              technology that is ever improving and is increasingly be-  Disclosures
              ing used in operational settings, both civilian and mili-
              tary. 27–29  While ultrasound is versatile, portable, easily   This case study was supported by Innovative Trauma
              repeatable, and without radiation, it is very user-depen-  Care, of which J. L. McKee is an employee. A. W.
              dent, which has, until recently, limited its use to highly   Kirkpatrick  received  the donation  of  the  NanoMaxx
              trained specialists with the time to learn all the skills and   portable ultrasound machine for unrestricted research
              pitfalls required to use ultrasound accurately. However,   purposes from the SonoSite Corporation.
              with global Internet availability, having remote experts
              who are able to guide on-scene novices through image   References
              acquisition, as well as to interpret the images in discus-  1.  Champion HR. Epidemiological basis for future improvements
              sion with the on-scene provider, is more practical. 7,30,31  in trauma care. Semin Hematol. 2004;41:173.



              Telementored US-Directed Compression in Vascular Injury                                         73
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